目的 对茄科中药白英(Solanum lyratum Thunb.)水提取物中的化学成分进行研究。方法 利用各种色谱法进行分离,根据理化性质和波谱数据鉴定结构。结果 从白英的水提取物中分离得到9个苯丙素类化学成分,分别鉴定为绿原酸(1)、隐绿原酸(2)、新绿原酸(3)、erythro-1,2-bis-(4-hydroxy-3-methoxyphenyl)-1,3-propanediol(4)、threo-1,2-bis-(4-hydroxy-3-methoxyphenyl)-1,3-propanediol(5)、erythro-2,3-bis-(4-hydroxy-3-methoxyphenyl)- 3-methoxypropanol(6)、threo-2,3-bis-(4-hydroxy-3-methoxyphenyl)-3-methoxypropanol(7)、丁香脂素(8)和鹅掌楸苷(9)。结论 除化合物1外,其余化合物均首次从该植物中分离得到。
Abstract
OBJECTIVE To study the chemical components of the aqueous extract of Solanum lyratum. METHODS The compounds were isolated and purified by column chromatography and their structures were elucidated by spectroscopic methods. RESULTS Nine phenylpropanoids were obtained from aqueous extracts of Solanum lyratum. The structures were determined as chlorogenic acid(1), crptochlorogenic acid(2), neochlorogenic acid(3), erythro-1,2-bis-(4-hydroxy-3- methoxyphenyl)-1,3-propanediol(4), threo-1,2-bis-(4-hydroxy-3-methoxyphenyl)-1,3-propanediol(5), erythro-2,3-bis-(4-hydroxy-3-methoxyphenyl)-3-methoxypropanol(6), threo-2,3-bis-(4-hydroxy-3- methoxyphenyl)-3-methoxypropanol(7), syringaresinol(8), and liriodendrin(9). CONCLUSION Compounds 2-9 are isolated from Solanum lyratum for the first time.
关键词
白英 /
水提取物 /
苯丙素类 /
结构鉴定
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Key words
Solanum lyratum /
aqueous extract /
phenylpropanoid /
structural identification
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中图分类号：
R284.1
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参考文献
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脚注
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基金
北京市自然科学基金资助项目(7154236);中日友好医院青年基金资助项目(2014-1-QN-2, 2014-2-QN-19)
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